Mastering the CLEP Biology Exam: Your Path to Earning College Credit Faster

CLEP Biology (College-Level Examination Program)

The College-Level Examination Program (CLEP) Biology exam provides an exceptional opportunity for students to earn college credits by demonstrating their knowledge of biology—without the need to take the course in a traditional classroom setting. Administered by the College Board, CLEP Biology allows learners to save time and tuition costs while advancing toward their academic goals.

Ideal for high school students, homeschoolers, adult learners, and military personnel, the CLEP Biology exam evaluates foundational understanding across a wide range of life science topics. From cell structure and molecular biology to ecology and evolution, this exam enables motivated learners to showcase their biological science proficiency and accelerate their path to a degree.

Free CLEP Biology Practice Test Online

Key Takeaways

  • CLEP Biology allows students to earn up to 6 college credits by passing a single exam.

  • It is designed for students who already have equivalent knowledge from prior study, work, or independent learning.

  • The exam covers molecular and cellular biology, organismal biology, and population biology/ecology.

  • It is computer-based, consisting of 115 multiple-choice questions to be completed in 90 minutes.

  • Offered year-round at approved test centers and eligible for remote proctoring in select cases.

Overview of CLEP and the Biology Exam

The CLEP (College-Level Examination Program) was created by the College Board to help learners demonstrate their knowledge in various subjects. With 30+ subject areas, CLEP is widely accepted by over 2,900 colleges and universities in the U.S.

CLEP Biology is among the most popular science offerings. The test is equivalent to a two-semester introductory college biology course, typically taken by science majors and non-majors alike. A strong performance on this exam can fulfill a lab science general education requirement at many institutions, allowing students to bypass entry-level coursework.

The exam is a great fit for:

  • High school students completing AP Biology or dual enrollment

  • Adult learners returning to college

  • Military members using DANTES-funded exams

  • Homeschoolers with strong biology instruction

What the CLEP Biology Exam Covers

CLEP Biology evaluates broad knowledge across major areas of life science. It consists of three main content categories:

1. Molecular and Cellular Biology (~33%)

  • Chemical and physical properties of living matter

  • Enzymes and metabolism

  • Cell structure and function

  • Cellular respiration and photosynthesis

  • Mitosis and meiosis

  • DNA replication, RNA transcription, and protein synthesis

  • Biotechnology and genetic engineering

2. Organismal Biology (~34%)

  • Structure and function of plants and animals

  • Comparative anatomy and physiology

  • Nutrition, digestion, and excretion

  • Nervous, muscular, and endocrine systems

  • Reproduction and development

  • Immune response

  • Homeostasis and regulatory mechanisms

3. Population Biology, Evolution, and Ecology (~33%)

  • Principles of evolution and natural selection

  • Population genetics

  • Ecosystems and energy flow

  • Biogeochemical cycles

  • Population dynamics and community interactions

  • Conservation biology and biodiversity

  • Human impact on the environment

Test Format and Scoring

The CLEP Biology exam is a computer-based test administered at official CLEP testing centers or through CLEP Remote Proctoring.

Test Details:

  • Number of Questions: 115

  • Time Limit: 90 minutes

  • Question Type: Multiple-choice

  • Scoring Scale: 20–80

  • Recommended Passing Score: Varies by institution (commonly 50)

  • Credits Earned: Up to 6 credits, depending on the institution

Scores are automatically calculated and delivered instantly (except for remote exams, which may take a few days). Each college sets its own credit-granting policies, so it’s essential to verify with your target school before scheduling the test.

Benefits of Taking CLEP Biology

1. Save Time and Tuition

By earning credit through CLEP, students can potentially skip two semesters of introductory biology, saving thousands in tuition and reducing the time needed to graduate.

2. Flexible Scheduling

CLEP exams are offered year-round, giving learners control over when and where they test.

3. Boost College Applications

Scoring well on CLEP Biology demonstrates academic initiative and scientific literacy—qualities that stand out on college and scholarship applications.

4. Supports Military Education

CLEP is fully funded for active-duty military, eligible veterans, and their spouses through DANTES, expanding educational access.

5. No Lab Requirement

Although CLEP Biology covers lab-equivalent topics, no physical lab work is needed—making it ideal for self-starters or remote learners.

Preparing for the CLEP Biology Exam

A strategic and well-paced study plan is essential. Here’s how to prepare effectively:

1. Review the Official CLEP Biology Study Guide

Available through the College Board, this guide outlines exam content, sample questions, and scoring details.

2. Use Free and Paid Online Resources

Leverage platforms such as:

  • Khan Academy (Biology content aligned to college standards)

  • Modern States (free CLEP prep and vouchers)

  • CLEP Practice Apps and flashcards

3. Practice with Sample Questions

Get comfortable with multiple-choice formats. Focus on elimination strategies and time management.

4. Take Diagnostic Practice Exams

Simulate test-day conditions to identify your strengths and weaknesses. Use results to target specific content areas for review.

5. Supplement with AP Biology Resources

AP Biology textbooks and prep guides are highly aligned with CLEP content and can be excellent supplemental study materials.

CLEP Credit Policies and College Acceptance

While CLEP Biology is widely accepted, credit-granting policies vary by institution. Some colleges award credit for a score of 50, others may require a higher score or provide fewer credits.

Before you test:

  • Use the College Board’s CLEP College Search tool to review your institution’s policies.

  • Contact the registrar or academic advisor at your target college to confirm credit equivalency.

  • Keep a copy of your score report and be prepared to request official transcripts from the College Board when enrolling.

Conclusion

The CLEP Biology exam provides a smart, efficient path for students to earn college credit and showcase biological science mastery. Whether you’re aiming to accelerate your degree, cut tuition costs, or strengthen your academic portfolio, CLEP Biology offers flexibility, affordability, and recognition.

With proper preparation and a clear understanding of the exam content, students from all backgrounds can confidently take the CLEP Biology exam and unlock new academic opportunities. In today’s fast-paced educational landscape, alternative credit programs like CLEP empower learners to take control of their future—and CLEP Biology is a powerful way to begin.

FAQs

Who should take the CLEP Biology exam?
Anyone with a strong understanding of biology—high school students, homeschoolers, adult learners, or military personnel—can take the exam to earn college credit.

How many college credits can I earn with CLEP Biology?
Most institutions grant 3–6 credits, equivalent to one or two semesters of introductory biology.

Is CLEP Biology harder than AP Biology?
CLEP Biology covers similar material to AP Biology, but focuses more on breadth than lab work. Difficulty depends on your preparation.

Can I retake the CLEP Biology exam if I fail?
Yes, but there is a three-month waiting period before you can retest.

Does CLEP Biology include lab work?
No. While the exam covers theoretical lab concepts, there is no hands-on lab requirement.